DYNASTAT 40MG POWDER FOR SOLUTION FOR INJECTION 10 VIALS

Management of Acute Pain: The recommended single or initial dose for treatment of acute pain is 40 mg, administered either IV. or IM., followed by 20 mg or 40 mg every 6 to 12 hours, as required, up to a maximum daily dosage of 80 mg. The IV bolus injection may be given directly into a vein or into an existing IV line. The IM injection should be given slowly and deeply into the muscle.
Concomitant Use with Opioid Analgesics: Opioid analgesics can be used concurrently with parecoxib, dosing as described previously. In clinical trials, the daily requirement for opioids was significantly reduced (20%-40%) when co-administered with parecoxib. An optimal effect is achieved when parecoxib is given prior to opioid administration. In all clinical assessments, parecoxib was administered at a fixed time interval whereas the opioids were administered on as needed basis (PRN).